The New England Journal of Medicine

peer-reviewed medical journal

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Pfizer's mRNA flu vaccine shows superior results in clinical trial
science Nov 19, 2025, 11:02 PM
Pfizer's mRNA flu vaccine shows superior results in clinical trial
  • In a Phase 3 trial, over 18,000 adults received either Pfizer's mRNA flu vaccine or a standard flu shot during the 2022-2023 flu season.
  • The mRNA vaccine showed approximately 27% higher efficacy than the traditional flu vaccine, although it also resulted in more side effects.
  • These findings indicate the mRNA shot's potential as a new approach for influenza prevention.
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