In November 2026, Fortune will host the Fortune 500 Innovation Forum in Detroit, Michigan. This significant event is aimed at bringing together a diverse group of influential figures, including CEOs, C-suite leaders from Fortune 500 companies, startup founders, investors, policymakers, nonprofit leaders, and cultural activists. Set for November 16 and 17, the Forum will explore new avenues for prosperity and innovation, underlining the theme "America Leads." This event will serve as the culminating point of a year-long editorial initiative focusing on key players and ideas that are poised to shape the future of business in America. The gathering will feature discussions on how some companies, which have survived for over a century, continue to thrive. Notably, it will also engage with the ongoing debates surrounding the U.S. economic landscape and innovation. While some experts voice concerns that the country is missing out on a significant era of innovation, others are optimistic that the right strategies are being developed to enhance growth and adaptability in a rapidly changing environment. The Forum not only provides a platform for dialogue among key stakeholders but also aims to encourage collaboration among diverse parties to stimulate growth in the economy. The participation of notable figures, including Fortune's editor-in-chief Alyson Shontell and various journalists, underlines the importance of this event in the context of the current economic climate. Together with the U.S. Chamber of Commerce and other strategic partners, Fortune is looking to spur conversation and ideas that will benefit the broader business landscape. This Forum is a crucial step in understanding how leaders can not only react to but also shape their evolving environments. Attendees are expected to walk away with insights that can influence their organizations and sectors, potentially contributing to an era of renewed innovation and prosperity for the United States. Through the concentrated efforts of Fortune and its partners, the Forum promises to be a significant highlight in the calendar of events aimed at reinvigorating the spirit of innovation across America.