In a recent episode of the podcast 'Bleep! With Ana Navarro,' Rosie O'Donnell discussed her experience with the weight-loss drug Mounjaro. The former talk show host revealed that she has been using the medication at a gradual pace, starting with the lowest dose of 2.5 milligrams for a year, then increasing to 5 milligrams for another year, and currently finishing a year at 7.5 milligrams. O'Donnell has successfully lost approximately 60 pounds over three years and plans to increase her dosage one more time before stabilizing it. She emphasized her preference for a slow weight loss process, as rapid weight loss has previously overwhelmed her. O'Donnell expressed satisfaction with her current health and noted that she has not experienced any side effects from the medication, including gastrointestinal issues that some users report. She mentioned that Mounjaro has significantly altered her relationship with food, leading to a reduced appetite and a shift in her beverage choices, moving away from Diet Cokes to primarily drinking water. O'Donnell has publicly praised Mounjaro, stating that it has 'saved' her life and expressed a desire to promote the drug to help others struggling with obesity. She highlighted the stigma and shame often associated with being overweight and conveyed her wish to support those facing similar challenges. O'Donnell's journey reflects a broader conversation about the effectiveness of weight-loss medications and the personal experiences of individuals navigating their health journeys.