In recent months, the Democratic Republic of the Congo (DRC) has faced a new Ebola outbreak, with the World Health Organization declaring it a public health emergency of international concern. The outbreak has raised alarm as it has already resulted in more than 860 suspected cases and over 200 deaths. Contributing to the severity of the situation is the fact that the Centers for Disease Control and Prevention (CDC) has been significantly weakened due to policy changes, leading to cuts in staffing and vacant senior leadership positions. This has left the agency struggling to mobilize an adequate response, with many experts describing the CDC as 'missing in action'. The ongoing Ebola outbreak has highlighted the deterioration of the U.S.’s commitment to global health infrastructure, which has been evident since the Trump administration began implementing an 'America First' policy in January 2025. This restructuring led to the termination of numerous USAID contracts and programs which were vital for outbreak preparedness and disease surveillance in various regions, including the DRC. During previous health crises, particularly the Ebola epidemic in West Africa, the U.S. played a critical role, committing more than $5.4 billion to support both domestic and international efforts. Now, however, the withdrawal from key international partnerships has left the nation isolated and ill-equipped to effectively handle new health threats. Furthermore, with an American citizen testing positive for Ebola and undergoing treatment in Germany, concerns about the potential for international transmission loom. The DRC has also experienced two confirmed cases that were linked to travel from the country's outbreak zone, including one fatality. This prompts a review of public health measures implemented by nations to prevent further spread as the risk remains classified as low domestically. Nevertheless, the situation is precarious, and experts warn that both localized and global systems for health response need to be strengthened. In response to the alarming numbers and rising concerns, the CDC’s leadership has publicly committed to international partnerships and ongoing support despite its internal limitations. Jennifer Nuzzo from the Pandemic Center raised issues regarding the drastic cuts and leadership gaps that have impeded decision-making, emphasizing that no federal agency can effectively function under such constraints. As of now, there is an urgent need to mobilize existing response infrastructure before the consequences become even more severe, as the Bundibugyo strain of Ebola presents unique challenges compared to past outbreaks.